Background: Many efforts have been invested in slowing progression of myopia. Among the methods, atropine\nadministration and orthokeratology (OK) are most widely used. This study analyzed the efficacy of atropine and OK\nlens in controlling myopia progression and elongation of axial length.\nMethods: This retrospective study included 105 patients (210 eyes) who wore OK lenses and 105 patients (210 eyes)\nwho applied 0.125% atropine every night during the 3 following period. Student t-test, linear regression analysis,\nrepeated measure ANOVA, and Pearsonâ��s correlation coefficient were used for statistical analysis.\nResults: The change in axial length per year was 0.28 �± 0.08 mm, 0.30 �± 0.09 mm, and 0.27 �± 0.10 mm in the OK lens\ngroup, and 0.38 �± 0.09 mm, 0.37 �± 0.12 mm, and 0.36 �± 0.08 mm in the atropine group for years 1, 2, and 3,\nrespectively. Linear regression analysis revealed an increase in myopia of 0.28 D and 0.34 D per year, and an increase in\naxial length of 0.28 mm and 0.37 mm per year in the OK lens and atropine groups, respectively. Repeated measure\nANOVA showed significant differences in myopia (p = 0.001) and axial length (p < 0.001) between the atropine and OK\nlens groups; in astigmatism, there was no significant difference in these parameters (p = 0.320). Comparison of\nincreases in axial length in relation to baseline myopia showed significant correlations both in the OK lens group\n(Pearsonâ��s correlation coefficient, r = 0.259; p < 0.001) and atropine group (r = 0.169; p = 0.014). High myopia patients\nbenefited more from both OK lenses and atropine than did low myopia patients. The correlation of baseline myopia\nand myopia progression was stronger in the OK lens group then in the atropine group.\nConclusions: OK lens is a useful method for controlling myopia progression even in high myopia patients.
Loading....